Korzhevskiĭ D E, Nikoleĭshvili M G, Otellin V A
Morfologiia. 2005;127(1):58-9.
Although typical astrocytic reaction to brain injury is accompanied by an increase of glial fibrillary acidic protein (GFAP) expression, to what degree this reaction is universal remains to be elucidated. The aim of the present study was to investigate the reaction of superficial glial limiting membrane of human brain to traumatic subarachnoid hemorrhage. Using light microscopy and immunocytochemistry, it was found that a suppresion of GFAP expression in astrocytes of superficial glial limiting membrane occurred up to 3 days following the brain trauma. The data obtained suggest the existence of regional peculiarities of astrocytic reaction.
尽管典型的星形胶质细胞对脑损伤的反应伴随着胶质纤维酸性蛋白（GFAP）表达的增加，但这种反应的普遍程度仍有待阐明。本研究的目的是调查人脑浅表胶质界膜对外伤性蛛网膜下腔出血的反应。通过光学显微镜和免疫细胞化学发现，脑外伤后3天内，浅表胶质界膜星形胶质细胞中的GFAP表达受到抑制。所获得的数据表明星形胶质细胞反应存在区域特殊性。
