亚硝酸盐可减轻大鼠胃黏膜中的脂质过氧化反应。
Nitrite mitigates lipid peroxidation in rat gastric mucosa.
作者信息
Grudziński Ireneusz P, Frankiewicz-Jóźko Anna, Szarska Ewa
机构信息
Department of Applied Physiology, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland.
出版信息
Rocz Panstw Zakl Hig. 2005;56(1):15-23.
PMID:16080441
Abstract
Sodium nitrite, a nitric oxide (NO) donor in the acid pH, has been found to mitigate lipid peroxidation in rat gastric mucosa, and it elevated both Cu, Zn- and Mn-forms of the superoxide dismutase in this tissue. Putrescine, a simple polyamine of anti-oxidant properties has been shown to normalize lipid peroxidation levels in nitrite-treated animals.
摘要
亚硝酸钠是一种在酸性pH值下能释放一氧化氮（NO）的物质，已发现它可减轻大鼠胃黏膜中的脂质过氧化反应，并且能提高该组织中铜锌超氧化物歧化酶和锰超氧化物歧化酶的水平。腐胺是一种具有抗氧化特性的简单多胺，已证明它能使经亚硝酸盐处理的动物的脂质过氧化水平恢复正常。
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