Blast2GO：功能基因组学研究中用于注释、可视化和分析的通用工具。
Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research.
作者信息
Conesa Ana, Götz Stefan, García-Gómez Juan Miguel, Terol Javier, Talón Manuel, Robles Montserrat
机构信息
Centro de Genómica, Instituto Valenciano de Investigaciones Agrarias, Moncada, Valencia, Spain.
出版信息
Bioinformatics. 2005 Sep 15;21(18):3674-6. doi: 10.1093/bioinformatics/bti610. Epub 2005 Aug 4.
SUMMARY
We present here Blast2GO (B2G), a research tool designed with the main purpose of enabling Gene Ontology (GO) based data mining on sequence data for which no GO annotation is yet available. B2G joints in one application GO annotation based on similarity searches with statistical analysis and highlighted visualization on directed acyclic graphs. This tool offers a suitable platform for functional genomics research in non-model species. B2G is an intuitive and interactive desktop application that allows monitoring and comprehension of the whole annotation and analysis process.
AVAILABILITY
Blast2GO is freely available via Java Web Start at http://www.blast2go.de.
SUPPLEMENTARY MATERIAL
http://www.blast2go.de -> Evaluation.
摘要
我们在此介绍Blast2GO（B2G），这是一种研究工具，其主要目的是能够对尚无GO注释的序列数据进行基于基因本体论（GO）的数据挖掘。B2G在一个应用程序中结合了基于相似性搜索的GO注释、统计分析以及在有向无环图上的突出可视化。该工具为非模式物种的功能基因组学研究提供了一个合适的平台。B2G是一个直观且交互式的桌面应用程序，可允许对整个注释和分析过程进行监测和理解。
可用性
可通过Java Web Start在http://www.blast2go.de上免费获取Blast2GO。
补充材料
http://www.blast2go.de -> 评估。
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