Dogomori H, Fujimoto T, Yoshimura N
Department of Anesthesia, Fujimoto Hospital, Miyakonojo.
Masui. 1992 May;41(5):817-21.
Using an MRI apparatus, we observed the effects of endotracheal intubation on the trachea by measuring T1 value before and after an operation in ten surgical cases. T1 value of the anterior wall at the level of the first tracheal ring was 275.8 +/- 58 msec, and that of the posterior wall was 346.8 +/- 72 msec. The patients were all intubated under general anesthesia. Anesthesia was maintained with inhalation anesthesia such as nitrous oxide-oxygen-enflurane with the aid of vecuronium bromide. Periods of intubation varied between 80 to 46 minutes, and averaged 270 +/- 112 minutes. After the extubation, T1 value showed 312 +/- 62 msec at the anterior wall and 395 +/- 82 msec at the posterior wall. In the case of the posterior wall, T1 value was significantly prolonged compared with that of the pre-intubation period. Prolongation of T1 value is assumed to be related to the increase of tissue free water demonstrating the occurrence of tissue edema. From the findings that T1 value might be prolonged by endotracheal intubation, we conclude that the MRI apparatus is useful for investigating the effects of the intubation procedure on the trachea.
我们使用磁共振成像（MRI）设备，通过测量10例手术病例手术前后的T1值，观察气管插管对气管的影响。气管第一环水平前壁的T1值为275.8±58毫秒，后壁的T1值为346.8±72毫秒。所有患者均在全身麻醉下进行插管。麻醉维持采用吸入麻醉，如氧化亚氮-氧气-安氟醚，并辅助使用溴化维库溴铵。插管时间在80至46分钟之间，平均为270±112分钟。拔管后，前壁T1值显示为312±62毫秒，后壁为395±82毫秒。在后壁的情况下，T1值与插管前相比显著延长。T1值延长被认为与组织游离水增加有关，表明组织水肿的发生。从T1值可能因气管插管而延长的发现来看，我们得出结论，MRI设备对于研究插管过程对气管的影响是有用的。
