Fomina I G, Iankin V V
Klin Med (Mosk). 1992 Jan;70(1):26-32.
Evolution of the effectiveness of antiarrhythmic drugs used in 240 patients with preexcitation syndrome to arrest episodes of paroxysmal supraventricular tachycardia was analysed prospectively. The first intravenous administration was effective in 97, 93.3, 80.9, 75, 70.3, 60, 48% of cases for novocainamid, verapamil, cordarone, disopyramide, ajmaline, ethacizine, mexitil and inderal, respectively. When observed in prospective evolution for 10-14 years, overall group efficacy dropped from 81.3% at first administration to 21.4%.
对240例预激综合征患者使用抗心律失常药物终止阵发性室上性心动过速发作的有效性演变进行了前瞻性分析。首次静脉给药时,新斯的明、维拉帕米、胺碘酮、丙吡胺、阿义马林、乙胺碘呋酮、美西律和心得安分别在97%、93.3%、80.9%、75%、70.3%、60%、48%的病例中有效。在前瞻性观察10 - 14年时,总体组疗效从首次给药时的81.3%降至21.4%。