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抗生素在慢性支气管炎急性加重期治疗中的作用(一些常见问题解答)

The role of antibiotics in the management of acute exacerbation of chronic bronchitis (answers to some commonly asked questions).

作者信息

Skudlarska B A, Scott G C

机构信息

Department of Medicine, University of Missouri-Columbia Hospital and Clinics.

出版信息

Mo Med. 1992 May;89(5):289-93.

PMID:1608387
Abstract

More than 7 million Americans suffer from chronic bronchitis, and it has been estimated that each of these patients will experience between one and four acute exacerbations a year. This problem constitutes a major social and financial burden on our society. Despite the prevalence of this disorder there is still considerable disagreement among physicians as to appropriate treatment, especially with regard to the use of antibiotics. Though the role of antibiotics is unclear, the pharmaceutical industry is trying to obtain regulatory approval of several new antibiotics for use in exacerbations of chronic bronchitis. We examine the role of antibiotics in the management of chronic bronchitis.

摘要

超过700万美国人患有慢性支气管炎,据估计,这些患者每人每年会经历1至4次急性加重。这个问题给我们的社会带来了重大的社会和经济负担。尽管这种疾病很普遍,但医生们对于适当的治疗方法,尤其是抗生素的使用,仍然存在很大分歧。虽然抗生素的作用尚不清楚,但制药行业正试图获得几种新抗生素用于慢性支气管炎加重期的监管批准。我们研究了抗生素在慢性支气管炎治疗中的作用。

相似文献

1
The role of antibiotics in the management of acute exacerbation of chronic bronchitis (answers to some commonly asked questions).抗生素在慢性支气管炎急性加重期治疗中的作用(一些常见问题解答)
Mo Med. 1992 May;89(5):289-93.
2
Con: antibiotic use in exacerbations of chronic bronchitis.反对观点:慢性支气管炎急性加重期使用抗生素。
Semin Respir Infect. 1993 Dec;8(4):254-8.
3
[Antibiotics in the treatment of exacerbations in patients with chronic bronchitis].[抗生素治疗慢性支气管炎患者的急性加重期]
Ugeskr Laeger. 1986 Jan 20;148(4):191-3.
4
Pro: antibiotics for chronic bronchitis with exacerbations.支持观点:用于慢性支气管炎急性加重期的抗生素。
Semin Respir Infect. 1993 Dec;8(4):243-53.
5
Chronic bronchitis.
Clin Chest Med. 1981 Jan;2(1):79-89.
6
[Acute and chronic bronchitis].
Ther Umsch. 1992 Apr;49(4):227-33.
7
Acute exacerbations of chronic bronchitis. Preventing treatment failures and early reinfection.慢性支气管炎急性加重。预防治疗失败和早期再感染。
Postgrad Med. 1994 Dec;96(8):75-6, 79-82, 87-9.
8
The use of antibiotics in acute bronchitis and acute exacerbations of chronic bronchitis.抗生素在急性支气管炎及慢性支气管炎急性加重期的应用。
West J Med. 1988 Sep;149(3):347-51.
9
Newer oral antimicrobials and newer etiologic agents of acute bronchitis and acute exacerbations of chronic bronchitis.急性支气管炎和慢性支气管炎急性加重期的新型口服抗菌药物及新型病原体
Semin Respir Infect. 1988 Mar;3(1):49-54.
10
The safety and efficacy of short course (5-day) moxifloxacin vs. azithromycin in the treatment of patients with acute exacerbation of chronic bronchitis.短期(5天)莫西沙星与阿奇霉素治疗慢性支气管炎急性加重患者的安全性和有效性。
Respir Med. 2000 Nov;94(11):1029-37. doi: 10.1053/rmed.2000.0927.

引用本文的文献

1
Efficacy and safety of a 10-day course of 400 or 600 milligrams of grepafloxacin once daily for treatment of acute bacterial exacerbations of chronic bronchitis: comparison with a 10-day course of 500 milligrams of ciprofloxacin twice daily.每日一次服用400毫克或600毫克格帕沙星,疗程为10天,用于治疗慢性支气管炎急性细菌感染的疗效和安全性:与每日两次服用500毫克环丙沙星,疗程为10天进行比较。
Antimicrob Agents Chemother. 1998 Jan;42(1):114-20. doi: 10.1128/AAC.42.1.114.