混合性结缔组织病：历经岁月，依旧复杂难辨
Mixed connective tissue disease: still crazy after all these years.
作者信息
Swanton Josephine, Isenberg David
机构信息
Centre for Rheumatology, University College London Hospitals, Arthur Stanley House, 40-50 Tottenham Street, London W1T 4NJ, UK.
出版信息
Rheum Dis Clin North Am. 2005 Aug;31(3):421-36, v. doi: 10.1016/j.rdc.2005.04.009.
Mixed connective tissue disease (MCTD) remains a controversial diagnosis. The classification criteria have changed significantly from the original description by Sharp and colleagues in 1972 after follow-up of the original and other MCTD patients. In this article we review the clinical, serologic, and genetic studies of MCTD published in the last 10 years and ask if this term is appropriate.
混合性结缔组织病（MCTD）仍然是一个有争议的诊断。自1972年夏普及其同事最初描述以来，经过对最初的以及其他MCTD患者的随访，分类标准已经发生了显著变化。在本文中，我们回顾了过去10年发表的关于MCTD的临床、血清学和遗传学研究，并探讨这个术语是否恰当。
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