Jouvencel P, Tourneux P, Pérez T, Sauret A, Nelson J R, Brissaud O, Demarquez J L
Service de pédiatrie et néonatologie, 13, avenue Interne J.-Loëb, centre hospitalier de la Côte Basque, 64100 Bayonne, France.
Arch Pediatr. 2005 Oct;12(10):1456-61. doi: 10.1016/j.arcped.2005.06.005. Epub 2005 Aug 9.
To evaluate the use of neonatal central venous catheters (CVC) in 38 french neonatal units and occurrence of pericardial effusion (PCE) over the past 5 years.
We surveyed 38 units with a questionnaire and studied the cases of PCE in five units.
Response rate was 89% (34/38). Accepted CVC tip positions were: junction of right atrium (RA) and vena cava (VC) 76%, VC 58%, RA 11%. Fifty percent of the centers had been exposed to PCE. 16 cases of PCE were studied. Median gestational age was 31 weeks (range: 26.1 to 40 weeks). Median time from insertion: 3.2 days (range: 0.4-13.5). In all cases CVC tip was intracardiac at insertion with inadequate withdrawing in 13 cases. Sudden cardiac collapse was reported in eight cases, and unexplained cardiorespiratory instability in six cases. Echography showed PCE in 14 cases. One diagnosis was post-mortem. CVC was withdrawn in 12 patients and 13 underwent pericardiocentesis. Four patients died and two had neurological sequelae.
PCE was associated with intracardiac CVC tip. The CVC tip should be controlled with radiography or echography outside the cardiac silhouette. PCE diagnosis must be considered in face of unexplained cardiovascular decompensation of neonate with CVC.
评估38个法国新生儿重症监护病房中新生儿中心静脉导管(CVC)的使用情况以及过去5年中心包积液(PCE)的发生率。
我们通过问卷调查了38个病房,并研究了其中5个病房的PCE病例。
回复率为89%(34/38)。可接受的CVC尖端位置为:右心房(RA)与腔静脉(VC)交界处76%,VC 58%,RA 11%。50%的中心曾发生过PCE。研究了16例PCE病例。中位胎龄为31周(范围:26.1至40周)。插入后的中位时间为3.2天(范围:0.4 - 13.5天)。所有病例在插入时CVC尖端均位于心腔内,其中13例回撤不足。8例报告有心脏骤停,6例有不明原因的心肺不稳定。超声检查显示14例有PCE。1例诊断为尸检后确诊。12例患者拔除了CVC,13例接受了心包穿刺术。4例患者死亡,2例有神经后遗症。
PCE与心腔内CVC尖端有关。CVC尖端应通过X线摄影或超声检查控制在心影之外。对于有CVC的新生儿出现不明原因的心血管失代偿时,必须考虑PCE的诊断。