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辅助受孕是产后情绪障碍和早期育儿困难的一个风险因素。

Assisted conception is a risk factor for postnatal mood disturbance and early parenting difficulties.

作者信息

Fisher Jane R W, Hammarberg Karin, Baker H W Gordon

机构信息

Key Centre for Women's Health in Society, School of Population Health, University of Melbourne, Melbourne, Victoria, Australia.

出版信息

Fertil Steril. 2005 Aug;84(2):426-30. doi: 10.1016/j.fertnstert.2005.02.016.

DOI:10.1016/j.fertnstert.2005.02.016
PMID:16084885
Abstract

OBJECTIVE

To investigate whether assisted conception is associated with an increased risk of admission to a residential early parenting program for treatment of maternal mood disorder or infant feeding or sleeping disorders in the postpartum year.

DESIGN

Systematic audit of consecutive medical records.

SETTING

Masada Private Hospital Mother Baby Unit (MPHMBU), Melbourne, Australia.

PATIENT(S): Medical records of all mother-infant dyads admitted to MPHMBU between July 2000 and August 2002.

INTERVENTION(S): None.

MAIN OUTCOME MEASURE(S): Modes of conception and delivery of index infant, maternal and infant age on admission, multiplicity of birth, infant birth weight, and Edinburgh Postnatal Depression Scale scores.

RESULT(S): A total of 745 records were audited, and mode of conception was recorded in 526 (70.6%) of records. Overall 6% (45/745) of the admitted infants had been conceived through assisted reproductive technologies compared with 1.52% in the general population (relative risk 4.0; 95% confidence interval, 3.0-5.4). Mothers who had conceived with assisted reproductive technologies were older and more likely to have had cesarean and multiple births than those who conceived spontaneously.

CONCLUSIONS

Assisted conception appears to be associated with a significantly increased rate of early parenting difficulties. Women who experience assisted conception may require additional support before and after their babies are born.

摘要

目的

探讨辅助受孕是否与产后一年内入住住院早期育儿项目以治疗产妇情绪障碍或婴儿喂养或睡眠障碍的风险增加有关。

设计

对连续的病历进行系统审核。

地点

澳大利亚墨尔本的马萨达私立医院母婴病房(MPHMBU)。

患者

2000年7月至2002年8月期间入住MPHMBU的所有母婴二元组的病历。

干预措施

无。

主要观察指标

索引婴儿的受孕和分娩方式、入院时的母婴年龄、出生多胎情况、婴儿出生体重以及爱丁堡产后抑郁量表评分。

结果

共审核了745份病历,其中526份(70.6%)记录了受孕方式。总体而言,6%(45/745)的入院婴儿是通过辅助生殖技术受孕的,而普通人群中的这一比例为1.52%(相对风险4.0;95%置信区间,3.0 - 5.4)。与自然受孕的母亲相比,通过辅助生殖技术受孕的母亲年龄更大,剖宫产和多胎分娩的可能性更高。

结论

辅助受孕似乎与早期育儿困难的发生率显著增加有关。经历辅助受孕的女性在宝宝出生前后可能需要额外的支持。

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