Total synthesis of scutellarin-7-O-glucuronide.
作者信息
Cui Jian-Mei, Fang Gang, Duan Ya-Bo, Liu Qian, Wu Li-Ping, Zhang Guo-Hong, Wu Song
机构信息
Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China.
出版信息
J Asian Nat Prod Res. 2005 Aug;7(4):655-60. doi: 10.1080/1028602032000169587.
PMID:16087641
Abstract
Scutellarin-7-O-glucuronide (1) has been synthesized from 2-hydroxyl-4,5,6-trimethoxyacetophenone through eight steps, including Michael addition, cyclization, hydrogenation, hydroxyl protection, deprotection, etc. The overall yield of 13% is much higher than that reported (0.6%) by L. Farkas, G. Mezey-Vàndor et al. in 1974.
摘要
Zotero 插件