Meiner Z, Newman J P, Rosenman H, Soffer D, Steiner I
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah University Hospital, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Neurology. 2005 Aug 9;65(3):478-80. doi: 10.1212/01.wnl.0000171347.28558.56.
Dementia with ubiquitinated neuronal inclusions has been described only with frontotemporal dementia (FTD). The authors report a patient with progressive FTD accompanied by prominent impairments in visuospatial cognitive functions. Pathology was characterized by ubiquitin-positive intranuclear and cytoplasmic neuronal inclusions. Cortical pathology was widespread and posteriorly accentuated but spared the hippocampal dentate gyrus.
伴有泛素化神经元包涵体的痴呆仅在额颞叶痴呆（FTD）中被描述过。作者报告了一名患有进行性FTD的患者，伴有明显的视觉空间认知功能障碍。病理学特征为泛素阳性的核内和胞质神经元包涵体。皮质病理广泛且在后部加重，但海马齿状回未受累。
