MacIntyre N R
Duke University Medical Center, Durham, North Carolina 27710, USA.
Semin Respir Crit Care Med. 2000;21(3):167-73. doi: 10.1055/s-2000-9851.
High-frequency ventilation (HFV) provides respiratory gas exchange using positive airway pressure-driven tidal breaths that are often smaller than anatomic dead space and breathing frequencies several times faster than normal. Gas transport with HFV involves nonconvective mechanisms such as Taylor dispersion, coaxial flow, and augmented diffusion. Devices to deliver HFV include the jet (an airway injector delivers jet pulses) and the oscillator (a piston oscillates a bias flow of fresh gas). The conceptual advantage to HFV is that maximal airway pressures are limited by the small tidal breath and lung recruitment is optimized by the intrinsic positive end expiratory pressure effect. Outcome has been shown to be improved in pediatric patients at risk for volutrauma. Adult outcome data are still lacking.
高频通气(HFV)通过气道正压驱动的潮气呼吸来实现呼吸气体交换,这些潮气通常小于解剖无效腔,呼吸频率比正常情况快几倍。HFV的气体传输涉及非对流机制,如泰勒弥散、同轴流和增强扩散。用于实施HFV的设备包括喷射器(气道注射器输送喷射脉冲)和振荡器(活塞使新鲜气体的偏流振荡)。HFV的概念优势在于,最大气道压力受小潮气呼吸限制,肺复张通过内在呼气末正压效应得到优化。已证明,有容积伤风险的儿科患者的治疗结果有所改善。成人的治疗结果数据仍然缺乏。