[2-merkaptobenzenosulfonamides derivates synthesis].

1,3-Dialkyl-2-[2-mercapto-4-R(1)-5-(carboxy- or cyano)benzenesulphonyl]guanidines (Va-g, VI; R(1)=Cl or H) were synthesized by reactions of 3-methylthio-, 3-mercapto- and 3-alkylamino-6-R(1)-7-(carboxy- or cyano)-1,4,2-benzoditiazine-1,1-dioxides with amines. Their oxidation (VII) or methylation products (VIlIa-c, IXa-c) as well novel 3-isobutylamino-6-chloro-7-R-1,4,2-benzodithiazine-1,1-dioxides (II, R=COCl; III, R=CONH2; IV, R=CN) which had been successfully used to the synthesis of compound VI, were also obtained.