Weitgenant Jeremy A, Mortison Jonathan D, Helquist Paul
Department of Chemistry and Biochemistry and Walther Cancer Research Center, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA.
Org Lett. 2005 Aug 18;7(17):3609-12. doi: 10.1021/ol050944z.
2-Substituted pyridine, quinoline, isoquinoline, bipyridine, and 1,10-phenanthroline analogues of benzylic acetates undergo SmI(2)-promoted coupling with aldehydes and ketones to afford (2-hydroxyalkyl)heteroaromatics. [reaction: see text]
苄基乙酸酯的 2-取代吡啶、喹啉、异喹啉、联吡啶和 1,10-菲咯啉类似物在二碘化钐促进下与醛和酮发生偶联反应,生成(2-羟烷基)杂芳烃。[反应:见正文]