Band Pierre R, Le Nhu D, MacArthur Amy C, Fang Raymond, Gallagher Richard P
Cancer Control Research Program, BC Cancer Agency, Vancouver, BC, Canada.
J Occup Environ Med. 2005 Aug;47(8):854-8. doi: 10.1097/01.jom.0000169094.77036.1d.
We collected information on lifetime occupational histories, smoking, and alcohol consumption from 15,463 incident cancer cases. Occupational risk factors for bladder cancer are presented in this report.
A matched case-control design was used. All cases were diagnosed with bladder cancers, with controls being internal controls consisting of all other cancer sites, excluding lung and unknown primary. Data were analyzed using conditional logistic regression for matched sets data and the likelihood ratio test.
Excess bladder cancer risks was observed in a number of occupation and industries, particularly those involving exposure to metals, including aluminum, paint and solvents, polycyclic aromatic hydrocarbons, diesel engine emissions, and textiles.
The results of our study are in line with those from the literature and further suggest that exposure to silica and to electromagnetic fields may carry an increased risk of bladder cancer.
我们收集了15463例新发癌症病例的终生职业史、吸烟和饮酒信息。本报告呈现了膀胱癌的职业风险因素。
采用配对病例对照设计。所有病例均被诊断为膀胱癌，对照为内部对照，由所有其他癌症部位组成，不包括肺癌和原发部位不明的癌症。使用条件逻辑回归对配对数据集进行数据分析，并进行似然比检验。
在一些职业和行业中观察到膀胱癌风险增加，特别是那些涉及接触金属、包括铝、油漆和溶剂、多环芳烃、柴油发动机排放物以及纺织品的职业和行业。
我们的研究结果与文献报道一致，进一步表明接触二氧化硅和电磁场可能会增加患膀胱癌的风险。
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