亚兹德省职业与膀胱癌风险：一项病例对照研究。
Occupations and the Risk of Bladder Cancer in Yazd Province: A Case-Control Study.
作者信息
Farzaneh Fatemeh, Mehrparvar Amir Houshang, Lotfi Mohammad Hassan
机构信息
Department of Epidemiology and Biostatistics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Industrial Diseases Research Center, Department of Occupational Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
出版信息
Int J Occup Environ Med. 2017 Oct;8(4):191-198. doi: 10.15171/ijoem.2017.1085.
BACKGROUND
Bladder cancer is the most common cancer of the urinary tract, with known occupational causes. The most effective way to prevent occupational cancers of the urinary tract is to prevent exposure to known carcinogens.
OBJECTIVE
To examine the relationship between occupation and the risk of bladder cancer.
METHODS
This case-control study was performed on 200 patients with bladder cancer and 200 healthy individuals in Yazd. Data were collected using a researcher-made questionnaire and based on interviews with patients and controls.
RESULTS
The mean age of cases and controls were 61.5 (SD 13.6) and 61.5 (13.3) years, respectively. Level of education, type of occupation, family history of bladder cancer in the first-degree relatives, and history of chronic and recurrent urinary tract infection, kidney and bladder stones, and using hair dye, were considered the main predictors for bladder cancer.
CONCLUSION
There was a significant difference between cases and controls in terms of type of occupation. The risk of bladder cancer was higher among those working in high-risk occupations-metal working, textile, driving, farming, and construction.
背景
膀胱癌是最常见的泌尿系统癌症，存在已知的职业病因。预防职业性泌尿系统癌症的最有效方法是防止接触已知致癌物。
目的
研究职业与膀胱癌风险之间的关系。
方法
在亚兹德对200例膀胱癌患者和200名健康个体进行了这项病例对照研究。通过研究者自制的问卷并基于对患者和对照的访谈收集数据。
结果
病例组和对照组的平均年龄分别为61.5（标准差13.6）岁和61.5（13.3）岁。教育程度、职业类型、一级亲属的膀胱癌家族史、慢性和复发性尿路感染病史、肾结石和膀胱结石病史以及使用染发剂，被认为是膀胱癌的主要预测因素。
结论
病例组和对照组在职业类型方面存在显著差异。从事高风险职业——金属加工、纺织、驾驶、农业和建筑行业的人群患膀胱癌的风险更高。
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