Liu Hong-Jian, Dong Ming-Min, Chi Fang-Lu
Department of Otorhinolaryngology, Eye and ENT Hospital of Fudan University, #83 Fenyang Road, Shanghai City 200031, PR China.
Laryngoscope. 2005 Aug;115(8):1418-20. doi: 10.1097/01.mlg.0000167982.07597.df.
To investigate the value of end-to-side neurorrhaphy to treat vocal cord paralysis.
A prospective study evaluating the effects of end-to-side neurorrhaphy to treat vocal cord paralysis by means of fiberoptic laryngoscopy and nerve electromyography.
Thirty Sprague-Dawley rats were divided into experimental group 1, experimental group 2, and a control group randomly. Right recurrent laryngeal nerve (RLN) was incised, and the distal end of the RLN was anastomosed to the right phrenic nerve by end-to-side neurorrhaphy in experimental group 1 or by end-to-end nerve anastomosis in experimental group 2, respectively. The adductor nerve branch of the right RLN was incised and anastomosed to the proximal end of the right ansa cervicalis nerve by end-to-end nerve anastomosis. Fiberoptic laryngoscopy and nerve electromyography were used to examine the vocal cord movement and nerve regeneration.
Three months after operation, this effect of end-to-side neurorrhaphy created a significant difference compared with the end-to-end nerve anastomosis (P < .05). The end-to-side neurorrhaphy did not lead to vocal cord movement compared with end-to-end nerve anastomosis.
Vocal cord paralysis cannot be treated by this microsurgical technique.
探讨端侧神经缝合术治疗声带麻痹的价值。
一项前瞻性研究，通过纤维喉镜检查和神经肌电图评估端侧神经缝合术治疗声带麻痹的效果。
将30只Sprague-Dawley大鼠随机分为实验组1、实验组2和对照组。切断右侧喉返神经（RLN），实验组1将RLN远端与右侧膈神经行端侧神经缝合，实验组2将RLN远端与右侧膈神经行端端神经吻合。切断右侧RLN的内收神经分支，并将其与右侧颈袢神经近端行端端神经吻合。采用纤维喉镜检查和神经肌电图检测声带运动及神经再生情况。
术后3个月，端侧神经缝合术与端端神经吻合术相比差异有统计学意义（P < .05）。与端端神经吻合术相比，端侧神经缝合术未引起声带运动。
该显微外科技术无法治疗声带麻痹。
