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人类狂犬病——佛罗里达州,2004年

Human rabies--Florida, 2004.

出版信息

MMWR Morb Mortal Wkly Rep. 2005 Aug 12;54(31):767-8.

Abstract

Rabies is a viral infection of the central nervous system, usually contracted from the bite of an infected animal, and nearly always fatal without postexposure prophylaxis. In February 2004, a man aged 41 years died after a 4-day hospitalization in Broward County, Florida. A diagnosis of rabies was considered on the day before the patient's death; however, no antemortem samples were obtained for testing. In March 2004, postmortem samples of fixed brain material were sent to CDC, where laboratory testing confirmed a diagnosis of rabies, the 47th case of human rabies reported in the United States since 1990 (CDC, unpublished data, 2005). This report summarizes results of the subsequent investigation led by the Broward County Health Department and laboratory testing at CDC, which determined that the rabies virus was a canine variant present in Haiti, where the man had traveled and reportedly been bitten by a dog. Rabies should be considered in persons after a dog bite, especially if the bite occurs in a country where canine rabies is enzootic.

摘要

狂犬病是一种中枢神经系统的病毒感染,通常通过感染动物的咬伤传播,如不进行暴露后预防,几乎总是致命的。2004年2月,一名41岁男子在佛罗里达州布劳沃德县住院4天后死亡。在患者死亡前一天考虑诊断为狂犬病;然而,未采集生前样本进行检测。2004年3月,固定脑材料的死后样本被送往美国疾病控制与预防中心(CDC),实验室检测确诊为狂犬病,这是自1990年以来美国报告的第47例人类狂犬病病例(CDC,未发表数据,2005年)。本报告总结了布劳沃德县卫生部门随后进行的调查结果以及CDC的实验室检测结果,这些结果确定狂犬病病毒是海地存在的犬类变种,该男子曾前往海地并据报被狗咬伤。狗咬伤后应考虑狂犬病,特别是如果咬伤发生在犬类狂犬病为地方病的国家。

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