Kasahata Naoki, Hasegawa Osamu, Tanaka Kyoko, Hanaue Kazuki, Terunuma Niina, Kamei Tetsumasa
Department of Neurology, Chigasaki Tokushukai General Hospital.
No To Shinkei. 2005 Jul;57(7):607-9.
A 68-year-old man presented with right eye pain and vertigo. Thereafter, he gradually leaned rightward, then laid down. He felt nausea and vomited. His right upper eyelid drooped and he felt dysethesia of the right hand. On neurological examination, ptosis of his right eye with slightly miotic right pupil, paresis of the right soft palate and hoarseness were noted. Arm deviation test demonstrated rightward deviation. He presented sensory ataxia of the right upper and lower extremities: finger nose test showed mild dysmetria of the right upper extremity, heel knee test demonstrated dysmetria of right lower extremity and these findings worsened when he closed his eyes. He showed mild bending of his bilateral ring and little fingers when he did rapid alternative movement. He leaned rightward when he sat and closed his eyes. Position sense of his right upper and lower extremities was decreased and sometimes he could not answer correctly when asked on which direction his finger pointed. Pinprick sensation was mildly decreased on the left side not including the face. Touch and vibration sense were normal. SEP findings on upper and lower extremity stimulation were normal. MRI of the brain showed T2 high intensity and partially T1 low intensity lesion at the right medulla (Figure). MR angiography showed no apparent lesion of major arteries such as dissection of the vertebral arteries. He complained and presented with hiccup initially. On MRI, the lesion was thought to involve the spinothalamic tract, medial lemniscus and inferior olivary nucleus. Ambiguus nucleus was in the lesion and solitary nucleus near the lesion. There is no report that seems to describe clinical features of a lesion like that in this case. Intermediate medullary infarction may present dissociated sensory disturbance like Brown-Sequard syndrome and position sensory disturbance without disturbance of vibration sense.
一名68岁男性出现右眼疼痛和眩晕。此后,他逐渐向右倾斜,然后躺下。他感到恶心并呕吐。他的右上眼睑下垂,右手感觉异常。神经系统检查发现右眼上睑下垂,右瞳孔略缩小,右软腭麻痹和声音嘶哑。上肢偏斜试验显示向右偏斜。他出现了右上肢和下肢的感觉性共济失调:指鼻试验显示右上肢轻度辨距不良,跟膝试验显示右下肢辨距不良,当他闭上眼睛时这些表现会加重。他在进行快速交替运动时双侧无名指和小指轻度弯曲。他坐着闭上眼睛时会向右倾斜。右上肢和下肢的位置觉减退,有时当被问及手指指向哪个方向时他无法正确回答。左侧(不包括面部)针刺觉轻度减退。触觉和振动觉正常。上下肢刺激的体感诱发电位结果正常。脑部MRI显示右侧延髓T2高信号和部分T1低信号病变(图)。磁共振血管造影显示主要动脉如椎动脉夹层等无明显病变。他最初抱怨并出现了打嗝。在MRI上,该病变被认为累及脊髓丘脑束、内侧丘系和下橄榄核。疑核位于病变内,病变附近有孤束核。似乎没有报告描述过这种病例中病变的临床特征。延髓中部梗死可能表现出像布朗 - 塞卡尔综合征那样的分离性感觉障碍以及位置觉障碍而无振动觉障碍。