Balabanova Y, Coker R, Fedorin I, Zakharova S, Plavinskij S, Krukov N, Atun R, Drobniewski F
Health Protection Agency National Mycobacterium Reference Unit, Department of Microbiology and Infection, Guy's, King's, and St Thomas' Medical School, London.
BMJ. 2005 Aug 13;331(7513):379-82. doi: 10.1136/bmj.331.7513.379.
To determine variability in interpretation of chest radiographs among tuberculosis specialists, radiologists, and respiratory specialists.
Observational study.
Tuberculosis and respiratory disease services, Samara region, Russian Federation.
101 clinicians involved in the diagnosis and management of pulmonary tuberculosis and respiratory diseases.
Interobserver and intraobserver agreement on the interpretation of 50 digital chest radiographs, using a scale of poor to very good agreement (kappa coefficient: < or = 0.20 poor, 0.21-0.40 fair, 0.41-0.60 moderate, 0.61-0.80 good, and 0.81-1.00 very good).
Agreement on the presence or absence of an abnormality was fair only (kappa = 0.380, 95% confidence interval 0.376 to 0.384), moderate for localisation of the abnormality (0.448, 0.444 to 0.452), and fair for a diagnosis of tuberculosis (0.387, 0.382 to 0.391). The highest levels of agreement were among radiologists. Level of experience (years of work in the specialty) influenced agreement on presence of abnormalities and cavities. Levels of intraobserver agreement were fair.
Population screening for tuberculosis in Russia may be less than optimal owing to limited agreement on interpretation of chest radiographs, and may have implications for radiological screening programmes in other countries.
确定结核病专家、放射科医生和呼吸科专家对胸部X光片解读的差异。
观察性研究。
俄罗斯联邦萨马拉地区的结核病和呼吸系统疾病服务机构。
101名参与肺结核和呼吸系统疾病诊断及管理的临床医生。
使用从差到非常好的一致性量表(kappa系数:≤0.20为差,0.21 - 0.40为一般,0.41 - 0.60为中等,0.61 - 0.80为好,0.81 - 1.00为非常好),评估50张数字化胸部X光片解读的观察者间和观察者内一致性。
对于是否存在异常的一致性仅为一般(kappa = 0.380,95%置信区间0.376至0.384),对于异常定位的一致性为中等(0.448,0.444至0.452),对于结核病诊断的一致性为一般(0.387,0.38到0.391)。一致性最高的是放射科医生。经验水平(该专业的工作年限)影响对异常和空洞存在情况的一致性。观察者内一致性水平为一般。
由于对胸部X光片解读的一致性有限,俄罗斯的结核病人群筛查可能并非最佳,这可能对其他国家的放射学筛查项目产生影响。