Divet A, Paesante S, Bleunven C, Anderson A, Treves S, Zorzato F
Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Italy.
J Muscle Res Cell Motil. 2005;26(1):7-12. doi: 10.1007/s10974-005-9001-1. Epub 2005 Oct 14.
The impact of calcium signaling on many cellular functions is reflected by the tight regulation of the intracellular Ca(2+) concentration that is ensured by diverse pumps, channels, transporters and Ca(2+) binding proteins. In this review, we present recently identified novel sarco(endo)plasmic reticulum proteins that may have a potential involvement in the regulation of Ca(2+) homeostasis in striated muscles.
钙信号对许多细胞功能的影响体现在细胞内Ca(2+)浓度的严格调控上,这是由多种泵、通道、转运体和Ca(2+)结合蛋白来确保的。在本综述中,我们介绍了最近鉴定出的新型肌浆(内质)网蛋白,它们可能参与调控横纹肌中的Ca(2+)稳态。