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新型肌浆(内质)网蛋白与横纹肌中的钙稳态

Novel sarco(endo)plasmic reticulum proteins and calcium homeostasis in striated muscles.

作者信息

Divet A, Paesante S, Bleunven C, Anderson A, Treves S, Zorzato F

机构信息

Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Italy.

出版信息

J Muscle Res Cell Motil. 2005;26(1):7-12. doi: 10.1007/s10974-005-9001-1. Epub 2005 Oct 14.

DOI:10.1007/s10974-005-9001-1
PMID:16096683
Abstract

The impact of calcium signaling on many cellular functions is reflected by the tight regulation of the intracellular Ca(2+) concentration that is ensured by diverse pumps, channels, transporters and Ca(2+) binding proteins. In this review, we present recently identified novel sarco(endo)plasmic reticulum proteins that may have a potential involvement in the regulation of Ca(2+) homeostasis in striated muscles.

摘要

钙信号对许多细胞功能的影响体现在细胞内Ca(2+)浓度的严格调控上,这是由多种泵、通道、转运体和Ca(2+)结合蛋白来确保的。在本综述中,我们介绍了最近鉴定出的新型肌浆(内质)网蛋白,它们可能参与调控横纹肌中的Ca(2+)稳态。

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本文引用的文献

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2
Intracellular Ca2+ dynamics in malignant hyperthermia and central core disease: established concepts, new cellular mechanisms involved.恶性高热和中央轴空病中的细胞内钙离子动态变化:既定概念及涉及的新细胞机制
Cell Calcium. 2005 Feb;37(2):121-7. doi: 10.1016/j.ceca.2004.08.001.
3
Dynamic alterations in myoplasmic Ca2+ in malignant hyperthermia and central core disease.恶性高热和中央轴空病中肌浆内钙离子的动态变化
构象肽探针 DP4 对电压钳制骨骼肌纤维中 DHPR 和 RyR1 钙通道双向信号传递的影响。
Biophys J. 2011 May 18;100(10):2367-77. doi: 10.1016/j.bpj.2011.04.012.
4
Minor sarcoplasmic reticulum membrane components that modulate excitation-contraction coupling in striated muscles.调节横纹肌兴奋-收缩偶联的小肌浆网膜成分。
J Physiol. 2009 Jul 1;587(Pt 13):3071-9. doi: 10.1113/jphysiol.2009.171876. Epub 2009 Apr 29.
Biochem Biophys Res Commun. 2004 Oct 1;322(4):1256-66. doi: 10.1016/j.bbrc.2004.08.031.
4
Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion.连接蛋白是由肌醇三磷酸受体激活和/或钙库耗竭诱导的钙内流的关键元件。
J Cell Biol. 2004 Aug 16;166(4):537-48. doi: 10.1083/jcb.200404079. Epub 2004 Aug 9.
5
Macromolecular complexes regulating cardiac ryanodine receptor function.调节心肌兰尼碱受体功能的大分子复合物
J Mol Cell Cardiol. 2004 Aug;37(2):417-29. doi: 10.1016/j.yjmcc.2004.05.026.
6
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Prog Biophys Mol Biol. 2004 May;85(1):33-69. doi: 10.1016/j.pbiomolbio.2003.07.001.
7
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News Physiol Sci. 2003 Dec;18:252-6. doi: 10.1152/nips.01458.2003.
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