Esaki Kazuki, Hamaoka Takafumi, Rådegran Göran, Boushel Robert, Hansen Jim, Katsumura Toshihito, Haga Shukoh, Mizuno Masao
Institute of Health and Sport Sciences, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8574, Japan.
Eur J Appl Physiol. 2005 Oct;95(4):361-70. doi: 10.1007/s00421-005-0008-5. Epub 2005 Oct 27.
It is not clear whether muscle oxygenation (O(2-NIRS)) measured by near-infrared spectroscopy (NIRS) correlates with femoral venous SO2 (S(fv)o2) during normoxic exercise. Therefore, the purpose of this study was to compare physiologically calibrated O(2-NIRS) with S(fv)o2 in subjects performing one-legged dynamic knee extension exercise (1L-KEE). Five healthy male subjects (age 25+/-2 year, height 177.8+/-4.8 cm, body weight 67.1 +/- 5.0 kg; mean +/- SD) performed 1L-KEE at 20, 40, and 60% of peak work rate (WR-peak) each for 4 min. S(fv)o2 was measured at rest and during the 3rd minute of each work rate. O(2-NIRS) was continuously monitored in a proximal region of the vastus lateralis (VL-p), a distal region of VL (VL-d), and a proximal region of the rectus femoris (RF-p). S(fv)o2 was 56.0% at rest and decreased to 36.6 at 20% WR-peak, 35.8 at 40% WR-peak, and 31.1 at 60% WR-peak. There was a significant correlation between O(2-NIRS) and S(fv)o2(VL-p: r (2) = 0.62, VL-d: r2 = 0.35, RF-p: r2 = 0.62, with a moderate variation among individuals at each site; residual values = 4.83 - 11.75). These data indicate that NIRS measurement provides a reflection of S(fv)o2 during 20-60% WR-peak of normoxic 1L-KEE.
在常氧运动期间，通过近红外光谱法（NIRS）测量的肌肉氧合作用（O(2-NIRS)）是否与股静脉血氧饱和度（S(fv)o2）相关尚不清楚。因此，本研究的目的是比较在进行单腿动态膝关节伸展运动（1L-KEE）的受试者中，经生理校准的O(2-NIRS)与S(fv)o2。五名健康男性受试者（年龄25±2岁，身高177.8±4.8厘米，体重67.1±5.0千克；平均值±标准差）在峰值工作率（WR-peak）的20%、40%和60%下进行1L-KEE，每次持续4分钟。在休息时以及每个工作率的第3分钟测量S(fv)o2。在股外侧肌近端区域（VL-p）、股外侧肌远端区域（VL-d）和股直肌近端区域（RF-p）连续监测O(2-NIRS)。休息时S(fv)o2为56.0%，在20% WR-peak时降至36.6，在40% WR-peak时降至35.8，在60% WR-peak时降至31.1。O(2-NIRS)与S(fv)o2之间存在显著相关性（VL-p：r(2)=0.62，VL-d：r2=0.35，RF-p：r2=0.62，每个部位个体间存在中度差异；残差值=4.83 - 11.75）。这些数据表明，在常氧1L-KEE的20%-60% WR-peak期间，NIRS测量可反映S(fv)o2。
