Hong L Elliot, Avila Matithew T, Wonodi Ikwunga, McMahon Robert P, Thaker Gunvant K
Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, Baltimore, MD 21228, USA.
Behav Res Methods. 2005 Feb;37(1):133-8. doi: 10.3758/bf03206407.
Smooth pursuit eye movement (SPEM) abnormalities are some of the most consistently observed neurophysiological deficits associated with genetic risk for schizophrenia. SPEM has been traditionally assessed by infrared or video oculography using laboratory-based fixed-display systems. With growing interest in using SPEM measures to define phenotypes in large-scale genetic studies, there is a need for measurement instruments that can be used in the field. Here we test the reliability of a portable, head-mounted display (HMD) eye movement recording system and compare it with a fixed-display system. We observed comparable, modest calibration changes across trials between the two systems. The between-methods reliability for the most often used measure of pursuit performance, maintenance pursuit gain, was high (ICC = 0.96). This result suggests that the portable device is comparable with a lab-based system, which makes possible the collection of eye movement data in community-based and multicenter familial studies of schizophrenia.
平稳跟踪眼球运动（SPEM）异常是与精神分裂症遗传风险相关的最常观察到的神经生理缺陷之一。传统上，SPEM是通过基于实验室的固定显示系统，使用红外或视频眼动描记法进行评估的。随着人们越来越有兴趣使用SPEM测量来定义大规模遗传研究中的表型，需要一种可在现场使用的测量仪器。在此，我们测试了一种便携式头戴式显示器（HMD）眼动记录系统的可靠性，并将其与固定显示系统进行比较。我们观察到两个系统在各试验之间有相当的、适度的校准变化。对于最常用的跟踪性能测量指标——维持跟踪增益，方法间的可靠性很高（组内相关系数=0.96）。这一结果表明，该便携式设备与基于实验室的系统相当，这使得在基于社区的精神分裂症多中心家族研究中收集眼动数据成为可能。
