Morishita M, Ohtsurut A, Nakashima M, Yamashita S
Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki City Nagasaki 852-8523, Japan.
Clin Oncol (R Coll Radiol). 2005 Aug;17(5):391-2. doi: 10.1016/j.clon.2005.02.005.
We report here a case of an atomic-bomb survivor with sequential, unilateral, multiple-organ primary tumours after exposure to direct external radiation. This 67-year-old woman was 8 years old when she was exposed to radiation from the atomic bomb. At the time of the explosion, she was in an open area, but hiding behind a tree, which shielded her left side. Therefore, the right side of her body was exposed to radiation directly and primarily. Since then, she has been diagnosed sequentially with breast cancer, ovarian tumour, thyroid tumour, head skin cancer and lung cancer. In each case, the tumour was on the right side of her body at the ages of 31, 38, 54, 58 and 64 years old, respectively. This case study indicates that the risk of multiple primary tumours should be considered in older atomic-bomb survivors.
我们在此报告一例原子弹幸存者病例，该患者在受到直接外部辐射后，出现了单侧、多器官的原发性肿瘤。这位67岁的女性在8岁时遭受了原子弹辐射。爆炸发生时，她身处空旷地带，但躲在一棵树后，这棵树遮挡了她的左侧身体。因此，她身体的右侧直接且主要受到了辐射。从那时起，她先后被诊断出患有乳腺癌、卵巢肿瘤、甲状腺肿瘤、头部皮肤癌和肺癌。在每种情况下，肿瘤分别出现在她31岁、38岁、54岁、58岁和64岁时身体的右侧。本病例研究表明，老年原子弹幸存者应考虑发生多原发性肿瘤的风险。
