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老年患者食管癌的手术治疗

[Surgery for cancer of the esophagus in elderly patients].

作者信息

Kajiyama Y, Tsurumaru M

机构信息

Department of Surgery, Juntendo University School of Medicine, Tokyo, Japan.

出版信息

Kyobu Geka. 2005 Jul;58(8 Suppl):756-61.

PMID:16097632
Abstract

Esophageal cancer has a fulminant biological characteristic, and shows a higher rate of lymph node metastasis than other gastrointestinal malignancies. The distribution of lymphatic spread is wide from cervical to abdominal field, and 3-field lymph node dissection is a standard procedure in esophageal cancer surgery. However, the morbidity and mortality rate following esophageal resection is higher than that of other gastrointestinal or thoracic surgery. The most serious postoperative complication of esophageal surgery in elderly patients is a pulmonary problem. In order to reduce postoperative pulmonary complications, we try to preserve bronchial artery, pulmonary branches of the vagal nerve, in addition to definite preservation of bilateral recurrent laryngeal nerve. Our survival rate and mean survival period in elderly patients with esophageal cancer was fairly good. To achieve a high survival rate and reduce postoperative morbidity and mortality in elderly patients, preoperative assessment of pulmonary function and quality control of surgical procedure is essential.

摘要

食管癌具有迅猛的生物学特性,并且相较于其他胃肠道恶性肿瘤,其淋巴结转移率更高。淋巴扩散的分布范围广泛,从颈部到腹部区域,而三野淋巴结清扫术是食管癌手术的标准术式。然而,食管癌切除术后的发病率和死亡率高于其他胃肠道或胸外科手术。老年患者食管癌手术最严重的术后并发症是肺部问题。为了减少术后肺部并发症,除了明确保留双侧喉返神经外,我们还尝试保留支气管动脉、迷走神经的肺分支。我们治疗老年食管癌患者的生存率和平均生存期相当不错。为了在老年患者中实现高生存率并降低术后发病率和死亡率,术前肺功能评估和手术操作的质量控制至关重要。

相似文献

1
[Surgery for cancer of the esophagus in elderly patients].老年患者食管癌的手术治疗
Kyobu Geka. 2005 Jul;58(8 Suppl):756-61.
2
[Esophageal cancer surgery; importance of surgical quality control].[食管癌手术;手术质量控制的重要性]
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3
[Lymph nodes dissection in esophageal cancer surgery].
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Intraoperative pathological investigation of recurrent nerve nodal metastasis can guide the decision whether to perform cervical lymph node dissection in thoracic esophageal cancer.术中对喉返神经旁淋巴结转移情况进行病理检查,可指导胸段食管癌是否行颈部淋巴结清扫的决策。
Oncol Rep. 2006 Nov;16(5):1061-6.
5
[Recent surgical treatment of thoracic esophageal carcinoma].[胸段食管癌的近期外科治疗]
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A prospective trial for avoiding cervical lymph node dissection for thoracic esophageal cancers, based on intra-operative genetic diagnosis of micrometastasis in recurrent laryngeal nerve chain nodes.一项基于术中对喉返神经链淋巴结微转移进行基因诊断的避免胸段食管癌颈淋巴结清扫的前瞻性试验。
J Surg Oncol. 2006 May 1;93(6):477-84. doi: 10.1002/jso.20453.
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[Ivor Lewis esophagectomy with two-field lymph node dissection for squamous cell carcinoma of the lower thoracic esophagus].[经腹-右胸两切口食管癌根治术联合二野淋巴结清扫治疗胸段下段食管鳞癌]
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8
[Significance of preservation of tracheal proper sheath at the time of cervical and upper mediastinal lymph node dissection for thoracic esophageal cancer].[胸段食管癌颈段及上纵隔淋巴结清扫时保留气管固有鞘膜的意义]
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9
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10
Effect of the number of lymph nodes sampled on postoperative survival of lymph node-negative esophageal cancer.取样淋巴结数量对淋巴结阴性食管癌患者术后生存的影响。
Cancer. 2008 Mar 15;112(6):1239-46. doi: 10.1002/cncr.23309.