Elito Julio, Han Kyung Koo, Camano Luiz
Department of Obstetrics, Escola Paulista de Medicina, Federal University of São Paulo, Rua Maria Carolina 68, CEP-01445-000, Jardim Paulistano, São Paulo, Brazil.
Acta Obstet Gynecol Scand. 2005 Sep;84(9):864-7. doi: 10.1111/j.0001-6349.2005.00836.x.
The hysterosalpingography (HSG) was evaluated after the clinical treatment of tubal pregnancy and the possible risk of tubal obstruction through the following parameters: beta-human chorionic gonadotropin (beta-hCG) levels, size of the adnexal mass, aspects of the image at ultrasound, and color Doppler.
Eighty patients were submitted to HSG after tubal pregnancy treatment from April 1994 to February 2002. Fifty received expectant management and 30 were treated with single-dose methotrexate (MTX) (50 mg/m(2) intramuscularly).
The patency of the ipsilateral tube was 84% and 78% after the MTX and expectant treatments, respectively (P > 0.05). After the logistic regression was performed, it was observed that levels of beta-hCG >5000 mUI/ml were directly related to the tubal obstruction risk, odds ratio = 11.79 (95% CI = 2.27-61.32). Other variables were not directly related to the tubal obstruction risk.
In this study, the probability of ipsilateral tubal obstruction depends on the beta-hCG levels. The increase in beta-hCG levels is followed by an enhancement in tubal obstruction risk. Therefore, the beta-hCG may be effective for the prognostic of the reproductive future of these patients.
通过以下参数评估输卵管妊娠临床治疗后的子宫输卵管造影（HSG）及输卵管阻塞的可能风险：β-人绒毛膜促性腺激素（β-hCG）水平、附件包块大小、超声图像表现及彩色多普勒。
1994年4月至2002年2月，80例输卵管妊娠治疗后的患者接受了HSG检查。50例接受期待治疗，30例接受单剂量甲氨蝶呤（MTX）（50mg/m²肌肉注射）治疗。
MTX治疗和期待治疗后同侧输卵管通畅率分别为84%和78%（P>0.05）。进行逻辑回归分析后发现，β-hCG水平>5000mIU/ml与输卵管阻塞风险直接相关，比值比=11.79（95%可信区间=2.27-61.32）。其他变量与输卵管阻塞风险无直接关系。
在本研究中，同侧输卵管阻塞的可能性取决于β-hCG水平。β-hCG水平升高后，输卵管阻塞风险增加。因此，β-hCG可能对这些患者的生殖预后有效。
