Quenot Jean-Pierre, Boichot Christophe, Petit Annie, Falcon-Eicher Sylvie, d'Athis Philippe, Bonnet Caroline, Wolf Jean-Eric, Louis Pierre, Brunotte François
Unité de Cardiologie Pédiatrique, Hôpital d'enfants et Centre de Cardiologie Clinique et Interventionnelle, Hôpital du Bocage, Dijon, France.
Int J Cardiol. 2005 Sep 1;103(3):312-6. doi: 10.1016/j.ijcard.2004.09.006.
The long-term outcome of repaired aortic coarctation may be complicated by dilatation of the ascending aorta notably in patients with bicuspid aortic valve. Magnetic resonance imaging was used to compare the size of the ascending aorta in patients with bicuspid or tricuspid aortic valve.
In 50 patients with a repair of aortic coarctation, the size of the ascending aorta was measured in a bicuspid aortic valve group (n=11) and a tricuspid aortic valve group (n=39). The aortic diameter was measured at the level of the sinus of Valsalva and at the widest part of the ascending aorta using magnetic resonance imaging.
The mean age of patients at surgical repair was respectively 2.2+/-3.3 years for the bicuspid aortic valve group and 2.5+/-3.5 years for the tricuspid aortic valve group (p=NS) and the mean age at the time of the magnetic resonance imaging was 10.2+/-4.7 years and 9.3+/-5.9 years (p=NS) respectively. A significant difference in the aortic diameter was found between the bicuspid aortic valve group and the tricuspid aortic group both at the level of sinus of Valsalva (34.8+/-8.2 mm, 19.5+/-4.4 mm, respectively, p<0.01) and at the level of the ascending aorta (36.8+/-7.2 mm, 16.9+/-3.4 mm, respectively, p<0.01).
The occurrence of ascending aortic dilatation is significantly associated with the presence of a bicuspid aortic valve. This requires long-term follow-up, which can be effectively performed by magnetic resonance imaging.
主动脉缩窄修复术后的长期预后可能因升主动脉扩张而复杂化，特别是在患有二叶式主动脉瓣的患者中。本研究采用磁共振成像比较二叶式或三叶式主动脉瓣患者升主动脉的大小。
在50例接受主动脉缩窄修复术的患者中，测量二叶式主动脉瓣组（n = 11）和三叶式主动脉瓣组（n = 39）的升主动脉大小。使用磁共振成像在主动脉瓣窦水平和升主动脉最宽处测量主动脉直径。
二叶式主动脉瓣组手术修复时患者的平均年龄为2.2±3.3岁，三叶式主动脉瓣组为2.5±3.5岁（p =无显著性差异），磁共振成像时的平均年龄分别为10.2±4.7岁和9.3±5.9岁（p =无显著性差异）。二叶式主动脉瓣组和三叶式主动脉瓣组在主动脉瓣窦水平（分别为34.8±8.2 mm和19.5±4.4 mm，p<0.01）和升主动脉水平（分别为36.8±7.2 mm和16.9±3.4 mm，p<0.01）的主动脉直径存在显著差异。
升主动脉扩张的发生与二叶式主动脉瓣的存在显著相关。这需要长期随访，磁共振成像可有效进行随访。
