Ahn Jung Yong, Chung Young Sun, Kwon Seong Oh, Huh Ryoong, Chung Sang Sup
Department of Neurosurgery, Pundang CHA Hospital, Pochon CHA University, Sungnam, South Korea.
J Clin Neurosci. 2005 Aug;12(6):691-3. doi: 10.1016/j.jocn.2004.09.010.
The pineal region is an unusual site for brain metastasis and most metastatic pineal lesions are asymptomatic. Rarely the symptoms of metastatic involvement of the pineal gland precede those of the primary tumor or other metastatic sites. An 83 year-old man presented with gait disturbance and limitation of upward gaze. Brain MRI showed homogeneous enhancement of a solitary mass in the pineal region with obstructive hydrocephalus. A stereotactic biopsy was performed, and small cell carcinoma was diagnosed. A systemic investigation for the primary lesion subsequently revealed small cell carcinoma of the lung. The patient was referred for radiotherapy and chemotherapy. Although rare, metastatic tumor should be considered in the differential diagnosis of pineal region tumors, particularly in elderly patients.
松果体区是脑转移瘤的一个不常见部位，大多数松果体转移瘤是无症状的。松果体转移瘤累及的症状很少先于原发肿瘤或其他转移部位出现。一名83岁男性出现步态障碍和向上凝视受限。脑部磁共振成像（MRI）显示松果体区有一个孤立肿块均匀强化，并伴有梗阻性脑积水。进行了立体定向活检，诊断为小细胞癌。随后对原发灶进行的全身检查发现了肺癌。该患者被转诊接受放疗和化疗。尽管罕见，但在松果体区肿瘤的鉴别诊断中应考虑转移瘤，尤其是在老年患者中。
