Chandra Sulekh, Gupta Nidhi, Gupta Rachna
Department of Chemistry, Zakir Husain College, University of Delhi, J.L. Nehru Marg, New Delhi 110002, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2006 Mar 1;63(3):587-93. doi: 10.1016/j.saa.2005.06.005. Epub 2005 Aug 10.
A series of five new copper(II) macrocyclic complexes have been synthesized by template condensation. The bonding and stereochemistry of the complexes have been characterized by elemental analysis, molar conductance, magnetic susceptibility, IR, UV-visible, EPR spectral studies and electrochemical properties. g-Values are calculated for all of the complexes in polycrystalline form as well as in DMSO solution. The magnetic and spectral data indicate square planar geometry for all the complexes. Cyclic voltammograms for all the complexes are similar and involve two quasi-reversible redox processes. Cu(II)Cu(II)<=>Cu(II)Cu(I)<=>Cu(I)Cu(I). Their biological properties have also been studied. The macrocyclic complexes show more anti-bacterial than controlled one. The anti-bacterial activities of the compounds were tested against Streptococcus fecalis and Escherichia coli with different concentrations.
通过模板缩合反应合成了一系列五种新型铜（II）大环配合物。通过元素分析、摩尔电导率、磁化率、红外光谱、紫外可见光谱、电子顺磁共振光谱研究和电化学性质对配合物的键合和立体化学进行了表征。计算了所有多晶形式以及二甲基亚砜溶液中配合物的g值。磁性和光谱数据表明所有配合物均为平面正方形几何结构。所有配合物的循环伏安图相似，涉及两个准可逆氧化还原过程。Cu（II）Cu（II）⇔Cu（II）Cu（I）⇔Cu（I）Cu（I）。还研究了它们的生物学性质。大环配合物显示出比对照物更强的抗菌活性。测试了这些化合物对不同浓度的粪链球菌和大肠杆菌的抗菌活性。
