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短期和长期肺康复对功能能力、呼吸困难感知及生活质量的影响。

The effects of short-term and long-term pulmonary rehabilitation on functional capacity, perceived dyspnea, and quality of life.

作者信息

Verrill David, Barton Cole, Beasley Will, Lippard W Michael

机构信息

NorthEast Medical Center Clinical Research Institute, Concord, NC, USA.

出版信息

Chest. 2005 Aug;128(2):673-83. doi: 10.1378/chest.128.2.673.

DOI:10.1378/chest.128.2.673
PMID:16100153
Abstract

STUDY OBJECTIVES

The purposes of this study were as follows: (1) to determine whether physical performance, quality of life, and dyspnea with activities of daily living improved following both short-term and long-term pulmonary rehabilitation (PR) across multiple hospital outpatient programs; (2) to examine the differences in these parameters between men and women; and (3) to determine what relationships existed between the psychosocial parameters and the results of the 6-min walk (6MW) test performance across programs.

DESIGN

Non-experimental, prospective, and comparative.

SETTING

Seven outpatient hospital PR programs from urban and rural settings across North Carolina.

PARTICIPANTS

Three hundred nine women and 281 men who were 20 to 93 years of age (mean [+/- SD] age, 66.7 +/- 11.1 years) with chronic lung disease.

INTERVENTIONS

All 6MW tests and health surveys were administered prior to and immediately following 12 and 24 weeks of supervised PR participation. Scores from the 6MW tests, the Ferrans and Powers quality of life index-pulmonary version III (QLI), the Medical Outcomes Study 36-item short form (SF-36), and the University of California at San Diego shortness of breath questionnaire (SOBQ) were compared at PR entry, at 12 weeks, and at 24 weeks for differences by gender with repeated-measures analysis of variance. The study entry and follow-up SF-36 physical and mental component summary scores, the QLI health/function and overall scores, and the SOBQ scores were also compared to the 6MW test scores with Pearson correlation coefficient analysis.

RESULTS

The mean summary scores on the SF-36 and the QLI increased after 12 weeks of PR (p < 0.05), and improvements were maintained by 24 weeks of PR participation (p < 0.05). Scores on the SOBQ improved after 12 weeks (p < 0.001) among the short-term participants, but not until after 24 weeks among the long-term participants (p = 0.009). The 6MW test performance improved after 12 weeks (p < 0.001) and again from 12 to 24 weeks (p = 0.002) in the long-term participants. No relevant correlational relationships were found between 6MW scores and the summary scores of the administered surveys (r = -0.43 to 0.36).

CONCLUSIONS

Physical performance, as measured by the 6MW test, continued to improve with up to 24 weeks of PR participation. Quality-of-life measures and the perception of dyspnea improved after 12 weeks of PR participation, with improvements maintained by 24 weeks of PR participation. It is recommended that PR patients participate in supervised PR for at least 24 weeks to gain and maintain optimal health benefits.

摘要

研究目的

本研究的目的如下:(1)确定在多个医院门诊项目中,短期和长期肺康复(PR)后,身体机能、生活质量以及日常生活活动中的呼吸困难情况是否得到改善;(2)检查男性和女性在这些参数上的差异;(3)确定跨项目的心理社会参数与6分钟步行(6MW)测试表现结果之间存在何种关系。

设计

非实验性、前瞻性和比较性研究。

地点

北卡罗来纳州城乡的七个门诊医院PR项目。

参与者

309名女性和281名男性,年龄在20至93岁之间(平均[±标准差]年龄为66.7±11.1岁),患有慢性肺病。

干预措施

在监督下参与PR的12周和24周之前及之后立即进行所有6MW测试和健康调查。通过重复测量方差分析,比较PR开始时、12周时和24周时6MW测试、费兰斯和鲍尔斯生活质量指数-肺部版本III(QLI)、医学结果研究36项简表(SF-36)以及加利福尼亚大学圣地亚哥分校气短问卷(SOBQ)的得分,以分析性别差异。还通过皮尔逊相关系数分析,将研究开始和随访时的SF-36身体和心理成分总结得分、QLI健康/功能和总体得分以及SOBQ得分与6MW测试得分进行比较。

结果

PR参与12周后,SF-36和QLI的平均总结得分增加(p<0.05),参与PR 24周后改善情况得以维持(p<0.05)。短期参与者中,SOBQ得分在12周后有所改善(p<0.001),但长期参与者直到24周后才有所改善(p = 0.009)。长期参与者中,6MW测试表现在12周后有所改善(p<0.001),从12周到24周再次改善(p = 0.002)。未发现6MW得分与所管理调查的总结得分之间存在相关关系(r = -0.43至0.36)。

结论

通过6MW测试衡量的身体机能在参与PR长达24周后持续改善。参与PR 12周后,生活质量指标和呼吸困难感知得到改善,参与PR 24周后改善情况得以维持。建议PR患者参与监督下的PR至少24周,以获得并维持最佳健康效益。

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