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一例因孤立性嗜酸性粒细胞性冠状动脉炎导致的心源性猝死病例。

A case of sudden cardiac death due to isolated eosinophilic coronary arteritis.

作者信息

Lepper Philipp M, Koenig Wolfgang, Möller Peter, Perner Sven

机构信息

Department of Internal Medicine II, University of Ulm, Robert-Koch-Str 8, 89081 Ulm, Germany.

出版信息

Chest. 2005 Aug;128(2):1047-50. doi: 10.1378/chest.128.2.1047.

Abstract

Spontaneous coronary artery dissection is a very rare event and occurs most often in young women following childbirth. It is also known as a rare focal complication in Churg-Strauss syndrome. Here, we present the case of a 43-year-old woman who died after spontaneous dissection of all three coronary arteries. The microscopic examination of coronary vessels showed severe eosinophilic infiltrations, whereas all extracardiac (medium-vessel and large-vessel) arteries were intact and free of inflammatory cells. Her history did not reveal allergy, asthma, or eosinophilia. To the best of our knowledge, this is the first case of spontaneous coronary dissection involving all coronary arteries without a history of Churg-Strauss syndrome or hypereosinophilic syndrome.

摘要

自发性冠状动脉夹层是一种非常罕见的事件,最常发生在产后的年轻女性中。它也是Churg-Strauss综合征中一种罕见的局灶性并发症。在此,我们报告一例43岁女性,该患者在所有三支冠状动脉均发生自发性夹层后死亡。冠状动脉的显微镜检查显示有严重的嗜酸性粒细胞浸润,而所有心外(中血管和大血管)动脉均完好无损且无炎症细胞。她的病史中未发现过敏、哮喘或嗜酸性粒细胞增多症。据我们所知,这是首例无Churg-Strauss综合征或高嗜酸性粒细胞综合征病史而累及所有冠状动脉的自发性冠状动脉夹层病例。

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