重症监护病房中呼吸道感染患者碳青霉烯类耐药非发酵革兰氏阴性杆菌的发生率。
Incidence of carbapenem resistant nonfermenting gram negative bacilli from patients with respiratory infections in the intensive care units.
作者信息
Gladstone P, Rajendran P, Brahmadathan K N
机构信息
Department of Clinical Microbiology, Christian Medical College, Vellore - 632 004, Tamil Nadu, India.
出版信息
Indian J Med Microbiol. 2005 Jul;23(3):189-91. doi: 10.4103/0255-0857.16593.
Resistance to carbapenems is commonly seen in nonfermenting gram negative bacilli (NFGNB). We document herein the prevalence of carbapenem resistance in NFGNB isolated from patients with respiratory tract infections in the intensive care units (ICUs). A total of 460 NFGNB were isolated from 606 endotracheal aspirate specimens during January through December 2003, of which 56 (12.2%) were found to be resistant to imipenem and meropenem. Of these, 24 (42.8%) were Pseudomonas aeruginosa , 8 (14.2%) were Acinetobacter spp. and 24 (42.8%) were other NFGNB. Stringent protocols such as antibiotic policies and resistance surveillance programs are mandatory to curb these bacteria in ICU settings
碳青霉烯类耐药性在非发酵革兰氏阴性杆菌（NFGNB）中很常见。我们在此记录了从重症监护病房（ICU）呼吸道感染患者中分离出的NFGNB中碳青霉烯类耐药性的流行情况。2003年1月至12月期间，从606份气管内吸出物标本中共分离出460株NFGNB，其中56株（12.2%）对亚胺培南和美罗培南耐药。其中，24株（42.8%）为铜绿假单胞菌，8株（14.2%）为不动杆菌属，24株（42.8%）为其他NFGNB。在ICU环境中，必须执行严格的方案，如抗生素政策和耐药性监测计划，以控制这些细菌。
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