Aydin Aysel, Yu Jian Q, Zhuang Hongming, Alavi Abass
Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Clin Nucl Med. 2005 Sep;30(9):606-7. doi: 10.1097/01.rlu.0000174200.67064.28.
The optimal management of patients with melanoma requires accurate imaging techniques that can screen the entire body for metastases. One of the most used tests for this purpose is bone scintigraphy. PET has been reported to be more sensitive than bone scintigraphy in some malignancies. In our case, FDG-PET was also superior to bone scintigraphy in detecting the extent of skeletal disease in a patient with melanoma. This is likely the result of the fact that metastasis to bone marrow may not result in bone reaction in certain conditions and therefore bone scans may remain negative despite skeletal involvement.
黑色素瘤患者的最佳管理需要精确的成像技术，以便对全身进行转移灶筛查。为此目的最常用的检查之一是骨闪烁显像。据报道，在某些恶性肿瘤中，PET比骨闪烁显像更敏感。在我们的病例中，FDG-PET在检测一名黑色素瘤患者的骨骼疾病范围方面也优于骨闪烁显像。这可能是因为在某些情况下，骨髓转移可能不会导致骨反应，因此尽管存在骨骼受累，骨扫描可能仍为阴性。
