Lu Jun, Hong Mei-Ling, Ji Shun-Jun, Teo Yong-Chua, Loh Teck-Peng
Key Lab. of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering of Suzhou University, Suzhou 215006, China.
Chem Commun (Camb). 2005 Sep 7(33):4217-8. doi: 10.1039/b507768k. Epub 2005 Jul 25.
In the presence of 20 mol% of chiral catalytic complex prepared from In(OTf)3 and chiral PYBOX, allyltributylstannane reacted with achiral ketones to afford the corresponding homoallylic alcohols in moderate to high enantioselectivities (54-95% ee), which constitutes the first example of enantioselective allylation of ketones catalyzed by the chiral In(III)-PYBOX complex.
在由三氟甲磺酸铟（In(OTf)3）和手性联吡啶二氧唑啉（PYBOX）制备的20摩尔%手性催化配合物存在下，烯丙基三丁基锡与非手性酮反应，以中等至高对映选择性（对映体过量值为54 - 95%）生成相应的高烯丙醇，这是手性铟（III）-联吡啶二氧唑啉（PYBOX）配合物催化酮的对映选择性烯丙基化反应的首个实例。
