Lawson K
Sheffield Hallam University, Division of Biomedical Sciences, School of Science and Mathematics, Pond Street, Sheffield, S1 1WB, UK.
IDrugs. 2000 Apr;3(4):373-6.
This meeting covered a broad range of pharmacological topics, although the main themes were covered in four mini-symposia. This report concentrates on the cannabinoid, pain and cardiac ischemia symposia. The cannabinoid system was identified as a major area of potential therapeutic interest, offering a number of clinical targets that may be modified through the actions of selective ligands. Novel approaches to the treatment of neurogenic pain, where conventional analgesics have limited value, are being explored with significant success. The role of delayed preconditioning in cardiac ischemia was also addressed as a mechanism of cardioprotection.
本次会议涵盖了广泛的药理学主题，尽管主要议题在四个小型专题讨论会上进行了探讨。本报告重点关注大麻素、疼痛和心脏缺血专题讨论会。大麻素系统被确定为一个具有潜在治疗意义的主要领域，提供了一些可通过选择性配体的作用进行调节的临床靶点。在传统镇痛药价值有限的神经源性疼痛治疗方面，正在探索新的方法，并取得了显著成功。延迟预处理在心脏缺血中的作用也作为一种心脏保护机制进行了讨论。
