肺移植后淋巴细胞性心肌炎。

Lymphocytic myocarditis after lung transplantation.

作者信息

Weinkauf Justin, Walia Rajat, Berry Gerald J, Vagelos Randall, Faul John L

机构信息

Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, California, USA.

出版信息

J Heart Lung Transplant. 2005 Aug;24(8):1163-5. doi: 10.1016/j.healun.2004.07.012.

DOI:10.1016/j.healun.2004.07.012

PMID:16102466

Abstract

This study reports the development of lymphocytic myocarditis in a bilateral lung allograft recipient. A 23-year-old woman developed congestive heart failure and severe left ventricular dysfunction 32 months after a bilateral lung allograft for cystic fibrosis. She had taken oral acyclovir for infectious mononucleosis that was diagnosed 11 months previously. Her viral load for Epstein-Barr virus (EBV) increased, and an echocardiogram revealed a left ventricular ejection fraction of 25% and endomyocardial biopsy revealed lymphocytic myocarditis. She received valacyclovir (1 g x 3 times daily) and made a full recovery 6 months later.

摘要

本研究报告了一名双侧肺移植受者发生淋巴细胞性心肌炎的情况。一名23岁女性在因囊性纤维化接受双侧肺移植32个月后出现充血性心力衰竭和严重左心室功能障碍。她曾因11个月前诊断出的传染性单核细胞增多症服用口服阿昔洛韦。她的爱泼斯坦-巴尔病毒（EBV）病毒载量增加，超声心动图显示左心室射血分数为25%，心内膜活检显示淋巴细胞性心肌炎。她接受了伐昔洛韦（每日3次，每次1 g）治疗，6个月后完全康复。