Lawson L, Yassin M A, Ramsay A, Emenyonu N E, Squire S B, Cuevas L E
Liverpool School of Tropical Medicine, Liverpool, UK.
Int J Tuberc Lung Dis. 2005 Aug;9(8):933-5.
To verify among tuberculosis (TB) suspects attending hospitals in Abuja, Nigeria, if sputum smears graded as scanty are false-positive, sputum smears from 1068 patients were graded with the International Union Against Tuberculosis and Lung Disease classification. One specimen was cultured. Eight hundred and twenty-four (26%) smears were positive, 137 (4%) scanty and 2243 negative. Of 1068 cultures, 680 (64%) were positive. One hundred and thirty (95%) scanty and 809 (98%) positive smears were culture-positive. Twelve of 18 patients with a single scanty smear and 51 of 52 with > or = 2 scanty smears were culture-positive. Fewer than < 5% scanty results, < 1% of the patients treated for TB, are false-positive.
为了验证在尼日利亚阿布贾医院就诊的结核病疑似患者中，分级为少量的痰涂片是否为假阳性，对1068例患者的痰涂片按照国际抗结核和肺病联盟的分类法进行分级。一份标本进行培养。824份（26%）涂片呈阳性，137份（4%）为少量，2243份为阴性。在1068份培养物中，680份（64%）呈阳性。130份（95%）少量涂片和809份（98%）阳性涂片培养呈阳性。18例仅有一份少量涂片的患者中有12例，52例有≥2份少量涂片的患者中有51例培养呈阳性。少量结果中假阳性的比例不到5%，接受结核病治疗的患者中假阳性比例不到1%。
