Cuoco Frank A, Singh Steven N
Department of Cardiology, Veterans Affairs Medical Center, 4A107, 50 Irving Street, NW, Washington, DC 20422, USA.
Curr Cardiol Rep. 2005 Sep;7(5):368-75. doi: 10.1007/s11886-005-0091-6.
In patients with structural heart disease, ventricular arrhythmias are associated with an increased risk of overall mortality and sudden cardiac death (SCD). Nonsustained ventricular tachycardia (NSVT) is common in patients with dilated cardiomyopathy of both ischemic and nonischemic origin. Recent studies suggest that NSVT may be a marker, but not a significant predictor, of mortality and SCD in that suppression of NSVT in these patients using antiarrhythmic drugs is of questionable benefit. Additionally, indications for implantable cardioverter defibrillator implantation do not include NSVT. This article focuses on the prognostic significance and treatment of patients with NSVT and ischemic or nonischemic dilated cardiomyopathy.
在患有结构性心脏病的患者中,室性心律失常与全因死亡率和心源性猝死(SCD)风险增加相关。非持续性室性心动过速(NSVT)在缺血性和非缺血性扩张型心肌病患者中很常见。最近的研究表明,NSVT可能是死亡率和SCD的一个标志物,但并非显著预测因素,因为使用抗心律失常药物抑制这些患者的NSVT的获益存疑。此外,植入式心脏复律除颤器植入的适应症不包括NSVT。本文重点关注NSVT合并缺血性或非缺血性扩张型心肌病患者的预后意义及治疗。