Sonnenfeld T, Nowak J, Cronestrand R, Aström H, Euler C V
Scand J Clin Lab Invest. 1979 Oct;39(6):577-84. doi: 10.3109/00365517909108836.
In twenty-four patients, undergoing a femoro-popliteal saphenous vein bypass graft for symptomatic atherosclerotic occlusion of the superficial femoral artery, oxygen saturation values for the femoral and popliteal veins were compared to the directly measured blood flows in the common femoral artery and in the bypass graft, respectively. Blood flow and venous oxygen saturation increased significantly after transfusion of 900 ml of blood. Pharmacological vasodilation caused a significant increase in blood flow both before and after transfusion, whereas the changes in venous oxygen saturation were significant only before blood transfusion. A close statistical relationship was found between initial femoral venous oxygen saturation and initial blood flow in the common femoral artery as well as between initial popliteal venous oxygen saturation and initial byapss blood flow. However, especially at low saturation values, the evaluation of blood flow was very uncertain. Whole leg and lower leg oxygen uptakes were not altered by intraoperative changes in blood volume. It is concluded that blood flow in the common femoral artery and the bypass graft can be roughly estimated from analysis of oxygen saturation in the femoral and popliteal veins, respectively. Furthermore, by determining leg venous oxygen saturation both before and after flow augmentation, induced by pharmacological vasodilation, a conception of the load on the vascular system may be obtained.
对24例因股浅动脉症状性动脉粥样硬化闭塞症而接受股腘隐静脉搭桥术的患者，分别将股静脉和腘静脉的氧饱和度值与股总动脉和搭桥移植物中直接测量的血流进行比较。输注900毫升血液后，血流和静脉氧饱和度显著增加。药物性血管舒张在输血前后均使血流显著增加，而静脉氧饱和度的变化仅在输血前显著。发现初始股静脉氧饱和度与股总动脉初始血流之间以及初始腘静脉氧饱和度与初始搭桥血流之间存在密切的统计关系。然而，尤其是在低饱和度值时，血流评估非常不确定。术中血容量变化未改变全腿和小腿的氧摄取量。得出的结论是，分别通过分析股静脉和腘静脉中的氧饱和度可大致估算股总动脉和搭桥移植物中的血流。此外，通过测定药物性血管舒张诱导的血流增加前后的腿部静脉氧饱和度，可了解血管系统的负荷情况。
