Hambleton Sophie, Arvin Ann M
Columbia University, Department of Pediatrics, New York, NY 10032, USA.
Adv Exp Med Biol. 2005;568:11-24. doi: 10.1007/0-387-25342-4_2.
The most compelling rationale for introducing universal vaccination against varicella was the predicted benefits to healthy children. Current evidence from the US experience indicates that these benefits are being realized. As is true for any new vaccine, implementation of such a program necessitates disease surveillance and modifications of the vaccine regimen as needed. In the case of VZV, the epidemiology of herpes zoster must be tracked as well as varicella disease trends. The prevention of herpes zoster may be another use of live attenuated or inactivated varicella vaccines.
引入水痘通用疫苗最令人信服的理由是预计对健康儿童有益。来自美国经验的当前证据表明这些益处正在实现。与任何新疫苗一样,实施这样一个项目需要进行疾病监测,并根据需要调整疫苗接种方案。就水痘带状疱疹病毒(VZV)而言,必须跟踪带状疱疹的流行病学以及水痘疾病趋势。预防带状疱疹可能是减毒活疫苗或灭活水痘疫苗的另一个用途。