Lacasse Yves, Montori Victor M, Lanthier Claude, Maltis Francois
Centre de Pneumologie, Hôpital Laval, 2725 Chemin-Sainte-Foy, Sainte-Foy, Quebec G1V 4G5, Canada.
Can Respir J. 2005 Jul-Aug;12(5):251-6. doi: 10.1155/2005/567975.
Health authorities create and maintain administrative databases. Despite the potential advantages of these databases, the validity of the information they include must be considered.
To examine the validity of diagnosing chronic obstructive pulmonary disease (COPD) from a large administrative database.
Physician services and prescription claims data related to COPD and asthma were extracted from the Quebec universal medical insurance register (Régie de l'assurance-maladie du Québec; RAMQ) from the period of April 1, 1994 to March 31, 1999. Before obtaining the data, criteria for the validity of the COPD diagnosis in the database were formulated based on the epidemiology of COPD in the province. The extent to which the database satisfied these criteria are described within the present paper.
For patients aged 65 years or older, COPD was two times more prevalent in the RAMQ database than in the 1994/1995 National Population Health Survey. One in three patients with a RAMQ-diagnosis of COPD also had a RAMQ-diagnosis of asthma, and 47% of patients aged 65 years or older with a RAMQ-diagnosis of COPD did not fill any prescription for beta-2-agonists. In addition, 42% of patients with a RAMQ-diagnosis of COPD who never had a RAMQ-diagnosis of asthma appeared only once with that diagnosis in the database. Of all patients aged 65 years or older with a RAMQ-diagnosis of COPD, 37% and 23% met the operational definitions of 'possible COPD' and 'probable COPD', respectively.
Most RAMQ-diagnoses of COPD lack validity; therefore, the validity of database diagnoses should be routinely ascertained before using administrative databases in clinical and health services research.
卫生当局创建并维护行政数据库。尽管这些数据库具有潜在优势,但必须考虑其中所包含信息的有效性。
从一个大型行政数据库中检验慢性阻塞性肺疾病(COPD)诊断的有效性。
从魁北克全民医疗保险登记处(Régie de l'assurance-maladie du Québec;RAMQ)提取1994年4月1日至1999年3月31日期间与COPD和哮喘相关的医生服务及处方申请数据。在获取数据之前,根据该省COPD的流行病学情况制定了数据库中COPD诊断有效性的标准。本文描述了数据库满足这些标准的程度。
在65岁及以上的患者中,RAMQ数据库中COPD的患病率是1994/1995年全国人口健康调查中的两倍。RAMQ诊断为COPD的患者中,三分之一同时也被RAMQ诊断为哮喘,且65岁及以上RAMQ诊断为COPD的患者中有47%未填写任何β-2-激动剂的处方。此外,RAMQ诊断为COPD但从未被RAMQ诊断为哮喘的患者中,42%在数据库中仅出现过一次该诊断。在所有65岁及以上RAMQ诊断为COPD的患者中,分别有37%和23%符合“可能的COPD”和“很可能的COPD”的操作定义。
大多数RAMQ对COPD的诊断缺乏有效性;因此,在临床和卫生服务研究中使用行政数据库之前,应常规确定数据库诊断的有效性。