丹麦结直肠癌手术后的30天死亡率。
Thirty-day mortality after surgery for colorectal cancer in Denmark.
作者信息
Nickelsen T N, Jørgensen T, Kronborg O
机构信息
Research Centre for Prevention and Health, Glostrup, Denmark.
出版信息
Colorectal Dis. 2005 Sep;7(5):500-6. doi: 10.1111/j.1463-1318.2005.00793.x.
OBJECTIVE
This study aimed to estimate the 30-day mortality after colorectal cancer (CRC) surgery in Denmark. Mortality was compared to other studies, and between departments, unadjusted and adjusted for case-mix.
MATERIALS AND METHODS
All patients in Denmark with a first-time colorectal adenocarcinoma operated between 1 May 2001 and 31 December 2002 were eligible, 5187 patients were included. Mortality was adjusted for age, sex, urgency, tumour location, Dukes' stage and ASA-score.
RESULTS
The 30-day mortality in Denmark after CRC-surgery was 9.9%. Adjusted for case-mix, four departments had significantly higher mortality than average. The variation between the 44 departments was significant both for radically operated (P = 0.02) patients and for all operated patients (P = 0.01).
CONCLUSION
The 30-day mortality in Denmark seems to be higher than in studies from other countries, but the lack of comparable nationwide studies makes it difficult to evaluate. To uncover the reasons for the departments to diverge significantly from average, further studies are needed.
目的
本研究旨在评估丹麦结直肠癌（CRC）手术后30天的死亡率。将该死亡率与其他研究进行比较，并在各科室之间进行比较，同时对病例组合进行未调整和调整后的比较。
材料与方法
丹麦所有在2001年5月1日至2002年12月31日期间首次接受结直肠腺癌手术的患者均符合条件，共纳入5187例患者。死亡率根据年龄、性别、紧急程度、肿瘤位置、杜克分期和美国麻醉医师协会（ASA）评分进行调整。
结果
丹麦CRC手术后30天的死亡率为9.9%。经病例组合调整后，四个科室的死亡率显著高于平均水平。44个科室之间在根治性手术患者（P = 0.02）和所有手术患者（P = 0.01）方面的差异均具有统计学意义。
结论
丹麦的30天死亡率似乎高于其他国家的研究结果，但由于缺乏全国性可比研究，难以进行评估。为了找出各科室与平均水平存在显著差异的原因，还需要进一步研究。
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