Kozhemiakin L A, Antonov V G, Kalikanov S A, Bondarenko I G, Pastushenkov V L
Biull Eksp Biol Med. 1992 Feb;113(2):138-9.
Xanthine oxidase activity has been revealed in human blood mononuclear cells. The enzyme is found in these cells only after solubilization. This may become the explanation for contradiction with other previous data claiming absence of xanthine oxidase in human blood mononuclears. The level of enzyme activity is 2.76 +/- 0.029 mu mol/g protein.min. The latter is readily inhibited with allopurinol and folic acid.
已在人血单核细胞中发现黄嘌呤氧化酶活性。该酶仅在细胞溶解后才在这些细胞中被发现。这可能解释了与之前其他声称人血单核细胞中不存在黄嘌呤氧化酶的数据之间的矛盾。酶活性水平为2.76±0.029微摩尔/克蛋白质·分钟。后者很容易被别嘌呤醇和叶酸抑制。
