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马舟状骨综合征三种常用治疗方法的定量比较。

Quantitative comparison of three commonly used treatments for navicular syndrome in horses.

作者信息

Schoonover Mike J, Jann Henry W, Blaik Margaret A

机构信息

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.

出版信息

Am J Vet Res. 2005 Jul;66(7):1247-51. doi: 10.2460/ajvr.2005.66.1247.

DOI:10.2460/ajvr.2005.66.1247
PMID:16111165
Abstract

OBJECTIVE

To quantitatively compare 3 commonly used treatments for navicular syndrome (NS) in horses: heel-elevation shoeing alone, heel-elevation shoeing and phenylbutazone administration, heel-elevation shoeing and injection of the distal interphalangeal joint (DIPJ) with triamcinolone acetonide (TA), and all 3 treatments in combination.

ANIMALS

12 horses with NS.

PROCEDURE

A force plate was used to measure baseline peak vertical ground reaction force (PVGRF) of the forelimbs. Each horse's forelimbs were shod with 3 degrees heel-elevation horseshoes; PVGRF was measured 24 hours and 14 days after shoeing. Fourteen days after shoeing (following data collection), phenylbutazone (4.4 mg/kg, i.v., q 12 h) was administered (5 treatments). Two hours after the fifth treatment, PVGRF was measured; TA (6 mg) was injected into the DIPJ of the forelimb that generated the lower baseline PVGRF Fourteen days later, PVGRF was measured. Phenylbutazone was administered as before, and PVGRF was measured. Percentage body weight of force (%BWF) was calculated from PVGRF measurements and used for comparisons.

RESULTS

14 days after shoeing, mean %BWF in both forelimbs significantly increased from baseline; additional administration of phenylbutazone significantly increased %BWF applied from the more lame forelimb. Compared with shoeing alone, there was no significant change in %BWF after injection of the DIPJ with TA in shod horses.

CONCLUSIONS AND CLINICAL RELEVANCE

Heel-elevation shoeing alone and in combination with phenylbutazone administration quantitatively decreased lameness in horses with NS. Although not significant, additional DIPJ injection with TA resulted in further quantitative decrease in lameness, compared with that achieved via shoeing alone.

摘要

目的

定量比较马舟骨综合征(NS)的3种常用治疗方法:单纯足跟抬高蹄铁术、足跟抬高蹄铁术与苯基丁氮酮给药、足跟抬高蹄铁术与用曲安奈德(TA)注射远侧指间关节(DIPJ),以及这3种治疗方法联合使用的效果。

动物

12匹患有NS的马。

步骤

使用测力板测量前肢的基线垂直地面峰值反作用力(PVGRF)。每匹马的前肢都装上3度足跟抬高蹄铁;装蹄后24小时和14天测量PVGRF。装蹄14天后(在收集数据之后),给予苯基丁氮酮(4.4毫克/千克,静脉注射,每12小时一次)(共5种治疗)。第5次治疗后2小时,测量PVGRF;将TA(6毫克)注射到产生较低基线PVGRF的前肢DIPJ中。14天后,测量PVGRF。像之前一样给予苯基丁氮酮,并测量PVGRF。根据PVGRF测量值计算力占体重的百分比(%BWF),并用于比较。

结果

装蹄14天后,两前肢的平均%BWF均较基线显著增加;额外给予苯基丁氮酮显著增加了跛行较重的前肢施加的%BWF。与单纯装蹄相比,给装蹄的马注射TA到DIPJ后,%BWF没有显著变化。

结论及临床意义

单纯足跟抬高蹄铁术以及与苯基丁氮酮联合使用可定量减轻患NS马的跛行。与单纯装蹄相比,额外注射TA到DIPJ虽不显著,但可使跛行进一步定量减轻。

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