Olofsson Jonas K, Broman Daniel A, Wulff Marianne, Martinkauppi Mikael, Nordin Steven
Department of Psychology, Umeå University, Sweden.
Physiol Behav. 2005 Sep 15;86(1-2):252-7. doi: 10.1016/j.physbeh.2005.07.022.
The purpose of the study was to better understand past findings of nasal chemosensory hypersensitivity in pregnant women by recording chemosensory event-related potentials (CSERPs) for information about cortical neuronal allocation (amplitudes) and temporal processing (latencies) of three concentrations of pyridine ranging from predominantly olfactory to trigeminal in activation in 15 pregnant and 15 non-pregnant women. CSERP components of primarily sensory (N1 and P2) and cognitive (P3) origin were evaluated. The results displayed no group differences in either N1 or P2 amplitudes or latencies, but tendencies of larger amplitudes and shorter latencies for P3 in pregnant women. This implies that pregnant women's hypersensitivity may more likely be referred to cognitive than sensory processing.
该研究的目的是通过记录化学感觉事件相关电位（CSERP），以更好地理解过去关于孕妇鼻化学感觉超敏反应的研究结果，这些电位用于获取15名孕妇和15名非孕妇对三种浓度吡啶的皮质神经元分配（振幅）和时间处理（潜伏期）的信息，这三种浓度的吡啶激活范围从主要嗅觉到三叉神经。评估了主要源于感觉（N1和P2）和认知（P3）的CSERP成分。结果显示，N1或P2的振幅和潜伏期在两组之间均无差异，但孕妇的P3有振幅更大和潜伏期更短的趋势。这意味着孕妇的超敏反应更可能与认知处理而非感觉处理有关。
