Santen Richard
University of Virginia, Charlottesville, USA.
Gynecol Endocrinol. 2005 Jul;21 Suppl 1:12-6. doi: 10.1080/09513590400030046.
Postmenopausal hormone therapy (HT) increases breast density, an effect that is rapidly reversed upon treatment discontinuation. Increased breast density is recognised to be a powerful risk factor for breast cancer. It is therefore important to know whether HT-induced changes in mammographic breast density can provide information about an individual's future risk of breast cancer; or whether an absence of any change in breast density following HT should be viewed as reassuring. Mammographic breast density therefore needs to be examined in further detail in order to better assess the risks of breast cancer in postmenopausal women and further individualize prescribing practices.
绝经后激素治疗（HT）会增加乳腺密度，这种影响在治疗停止后会迅速逆转。乳腺密度增加被认为是乳腺癌的一个强大风险因素。因此，了解HT引起的乳腺钼靶密度变化是否能提供个体未来患乳腺癌风险的信息，或者HT后乳腺密度没有任何变化是否应被视为令人安心，这一点很重要。因此，需要进一步详细研究乳腺钼靶密度，以便更好地评估绝经后女性患乳腺癌的风险，并进一步使处方实践个性化。
