Sivakumar S, Mathews Mary S, George Biju
Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Mycoses. 2005 Sep;48(5):360-2. doi: 10.1111/j.1439-0507.2005.01139.x.
Cunninghamella bertholletiae, a rare causative agent of mycosis among immunocompromised patients has been reported with increased frequency from western countries in recent years. We report a case of C. bertholletiae pulmonary infection in a 42-year-old male patient who developed graft-vs.-host disease following bone marrow transplantation. In spite of intensive antifungal chemotherapy following clinical diagnosis, he died of pulmonary failure. To our knowledge this is the first report from India and third report of post-BMT C. bertholletiae infection ever published.
柏氏小克银汉霉是免疫功能低下患者中罕见的真菌病病原体,近年来西方国家报道其发病率有所增加。我们报告一例42岁男性患者发生柏氏小克银汉霉肺部感染,该患者在骨髓移植后发生移植物抗宿主病。尽管临床诊断后进行了强化抗真菌化疗,但他仍死于呼吸衰竭。据我们所知,这是来自印度的首例报告,也是有史以来发表的第三例骨髓移植后柏氏小克银汉霉感染报告。