Modarai B, Dasgupta P, Taylor J, Koffman G, Khan M S
Department of Urology, Guy's and St. Thomas' Hospitals, Thomas Guy House, London, UK.
Int J Clin Pract. 2005 Sep;59(9):1005-7. doi: 10.1111/j.1742-1241.2005.00577.x.
The polytetrafluoroethylene (PTFE) arteriovenous fistula allows vascular access for haemodialysis where a primary fistula or brachio-basilic vein transposition is not possible. We report patency rates and complications associated with these prosthetic grafts. Fifty-nine upper limb PTFE grafts in 48 patients were evaluated with a mean follow-up of 19 months (range 2-54 months). Three grafts (5%) were never used. The primary patency rate at 6 weeks was 90%. Cumulative secondary patency rates were 66% at 6 months, 36% at 12 months, 17% at 18 months, 3% at 24 months and 2% at 30 months. None of the grafts had remained patent at 3 years. Forty-six percent of the grafts studied thrombosed at least once and 32% became infected. Although the initial primary patency rate achieved compares favourably with that reported for brachio-basilic transposition fistulae, this study confirms that the use of prosthetic material is associated with a poor overall patency rate and high risk of complications. All options using autologous vein should be exhausted before considering prosthetic material.
聚四氟乙烯(PTFE)动静脉内瘘可在无法建立自体动静脉内瘘或进行肱动脉-贵要静脉转位术时提供血管通路以进行血液透析。我们报告了这些人工血管移植物的通畅率及相关并发症。对48例患者的59条上肢PTFE移植物进行了评估,平均随访19个月(范围2 - 54个月)。3条移植物(5%)从未使用过。6周时的初次通畅率为90%。6个月时的累计二次通畅率为66%,12个月时为36%,18个月时为17%,24个月时为3%,30个月时为2%。3年时无一例移植物仍保持通畅。所研究的移植物中有46%至少发生过一次血栓形成,32%发生感染。尽管所达到的初始初次通畅率与肱动脉-贵要静脉转位内瘘所报告的通畅率相比具有优势,但本研究证实使用人工材料与总体通畅率低及并发症风险高相关。在考虑使用人工材料之前,应先穷尽所有使用自体静脉的方案。