Barnes N C, Williams A E
Department of Respiratory Medicine, London Chest Hospital, London.
Int J Clin Pract. 2005 Sep;59(9):1017-24. doi: 10.1111/j.1742-1241.2005.00615.x.
This survey describes asthma control and unscheduled healthcare resource use (HCRU) among patients receiving low-dose inhaled corticosteroids (ICS) alone in five European countries and the USA. Physicians and patients completed forms collecting data on asthma symptoms, sudden increase in chest/respiratory symptoms, asthma-related HCRU, quality of life (QoL) and drug therapy. Fifty-seven per cent of patients on low-dose ICS alone had physician-rated moderate or severe asthma. Only 13% of patients receiving low-dose ICS alone achieved asthma control; 36% reported nocturnal wakening and 22% reported unscheduled healthcare services in the past year. Gender, symptom frequency, episodes of sudden increase in chest/respiratory symptoms and impaired QoL were all related to unscheduled healthcare resource utilisation. Many patients receiving low-dose ICS alone do not have adequate asthma control. Some patient characteristics were found to be significantly different, but not exclusive, between unscheduled healthcare resource users and non-users.
这项调查描述了在五个欧洲国家和美国仅接受低剂量吸入性糖皮质激素(ICS)治疗的患者的哮喘控制情况以及非计划医疗资源使用(HCRU)情况。医生和患者填写了表格,收集有关哮喘症状、胸部/呼吸道症状突然加重、与哮喘相关的医疗资源使用、生活质量(QoL)和药物治疗的数据。仅接受低剂量ICS治疗的患者中,57%的患者被医生评定为患有中度或重度哮喘。仅接受低剂量ICS治疗的患者中只有13%实现了哮喘控制;36%的患者报告有夜间觉醒,22%的患者报告在过去一年中使用了非计划医疗服务。性别、症状频率、胸部/呼吸道症状突然加重的发作次数以及生活质量受损均与非计划医疗资源利用有关。许多仅接受低剂量ICS治疗的患者哮喘控制不佳。在非计划医疗资源使用者和非使用者之间,发现一些患者特征存在显著差异,但并非唯一差异。