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一项关于哮喘管理中治疗失败情况的跨国研究。

A multinational study of treatment failures in asthma management.

作者信息

Burney P, Potts J, Aït-Khaled N, Sepulveda R M D, Zidouni N, Benali R, Jerray M, Musa O A A, El-Sony A, Behbehani N, El-Sharif N, Mohammad Y, Khouri A, Paralija B, Eiser N, Fitzgerald M, Abu-Laban R

机构信息

Department of Respiratory Epidemiology and Public Health, National Heart and Lung Institute, Imperial College, London, UK.

出版信息

Int J Tuberc Lung Dis. 2008 Jan;12(1):13-8.

Abstract

SETTING

Emergency rooms.

OBJECTIVE

To assess quality of care and its determinants for asthma patients before emergency room treatment.

DESIGN

Consecutive patients with acute severe asthma attending emergency rooms were questioned about the severity of their disease and treatment in the previous 4 weeks. Prescriptions of inhaled corticosteroids were recorded. Other outcomes included self-reported adherence to treatment and loss of work.

RESULTS

Thirteen centres in 11 countries recruited 1156 patients. Only 36% of patients with persistent asthma had been prescribed an adequate dose of inhaled corticosteroids. This percentage improved in those receiving regular care from the same doctor (OR 2.86, 95%CI 1.38-5.96), and was at least as good for the 10% of patients receiving 'private' health care (OR 3.08, 95%CI 1.69-5.62). Forty-four per cent of patients had health insurance covering some asthma medications. These patients were more likely to be receiving adequate inhaled corticosteroids (OR 1.74, 95%CI 1.17-2.58), and reported better adherence than those without insurance (OR 3.00, 95%CI 1.64-5.50). Of those on adequate inhaled corticosteroids, 18% had lost work in each of the 4 previous weeks compared with 59% among those more than one treatment step below the recommended dose.

CONCLUSIONS

Access to adequate treatment is critical for better management of asthma.

摘要

研究背景

急诊室。

研究目的

评估急诊室治疗前哮喘患者的护理质量及其决定因素。

研究设计

对连续就诊于急诊室的急性重症哮喘患者询问其疾病严重程度及过去4周的治疗情况。记录吸入性糖皮质激素的处方。其他结果包括自我报告的治疗依从性和工作损失情况。

研究结果

11个国家的13个中心招募了1156名患者。仅有36%的持续性哮喘患者被处方了足够剂量的吸入性糖皮质激素。在那些接受同一位医生定期护理的患者中,这一比例有所提高(比值比2.86,95%置信区间1.38 - 5.96),对于10%接受“私人”医疗保健的患者来说至少同样良好(比值比3.08,95%置信区间1.69 - 5.62)。44%的患者有涵盖某些哮喘药物的健康保险。这些患者更有可能接受足够剂量的吸入性糖皮质激素治疗(比值比1.74,95%置信区间1.17 - 2.58),并且报告的依从性比没有保险的患者更好(比值比3.00,95%置信区间1.64 - 5.50)。在接受足够剂量吸入性糖皮质激素治疗的患者中,在过去4周里,每周有18%的人有工作损失,而在低于推荐剂量一个以上治疗步骤的患者中这一比例为59%。

研究结论

获得充分治疗对于更好地管理哮喘至关重要。

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